The Holy Family Red Crescent Medical College started its journey in the academic year 1999-2000 with active inspiration of the then Prime Minister Sheikh Hasina. The then Health Minister Sheikh Fazlul Karim Salim MP, Chairman, Bangladesh Red Crescent Society Sheikh Kabir Hossain and all the Doctors and Staffs working in Holy Family Red Crescent Medical College Hospital under the leadership of Professor Dr. Md. Maniruzzaman Bhuiyan contributed tremendously to establish the College. 

The Holy Family Red Crescent Medical College is a project of Bangladesh Red Crescent Society (BDRCS) and is run by a Governing Body duly formed by the representatives of sponsor organization Bangladesh Red Crescent Society (BDRCS), representatives from Dhaka University and Government of Bangladesh.

The College follows the course curriculum of MBBS course as laid down by Dhaka University and Bangladesh Medical and Dental Council. Government of Bangladesh regulates the criteria of qualification of students and Dhaka University conducts the professional examinations and certificates of MBBS degree are awarded by them.

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